Despite Israel enjoying close ties with the Trump administration over a number of diplomatic issues, Netanyahu's refusal to take the debate reflects the precarious position in which Trump has foudn himself in the run-up to the November 3 election.
Trump currently lags in the polls behind Biden, with some observers contending that Netanyahu has increasingly attempted to distance himself from the US incumbent as the election draws closer.
Under Trump's presidency, the US took the unprecedented step of recognising Jerusalem as Israel's capital, breaking with decades of convention. The move sparked a backlash from Arab and Muslim states, while also triggering protests around the world and in the Palestinian territories.
The Trump administration also slashed crucial funding to the UN's agency for Palestinian refugees, the UN Relief and Works Agency (UNRWA).
Until the announcement in 2018, the US was the largest single contributor to the agency, paying $1.1 billion of UNRWA's annual budget.
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