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Syrian regime troops and fighters from Iran, alongside Lebanon's Hizballah, backed by Russian airstrikes, had launched a major offensive against the eastern and western suburbs of Damascus on Thursday, October 29.
Turkey summons Russian ambassador
Meanwhile, Turkey has summoned Russia's ambassador in protest at the "intensive" bombing of Turkmen villages in northern Syria by Russian warplanes, Prime Minister Ahmet Davutoglu told reporters on Friday.
The Turkish foreign ministry said in a separate statement that the attacks targeting civilian Turkmen villages "could lead to serious consequences", and called for an immediate end to the operation.
Russia continued on Friday to ramp up its bombardment of Syria, firing cruise missiles at both Islamic State and rebel-held areas from vessels in the Mediterranean Sea and long-range strategic bombers.
The Syrian Observatory for Human Rights and activist media outlets on Friday reported a large barrage of missile attacks striking rebel-held areas of the Idlib and Hama province, where IS has no military presence.
Moscow on Tuesday significantly upped the tempo of its aerial campaign in Syria after announcing that it now believed Metrojet Flight 9268 was brought down over the Sinai by a terrorist attack, for which IS earlier claimed responsibility.
The Russian Defence Ministry has since touted that it conducted three "massive" waves of airstrikes against so-called IS targets in Syria.
Moscow said that long-range Tu-22M3 bombers, taking off from Russia, had launched cruise missiles in conjunction with airstrikes from Latakia-based Russian fighter jets.
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Meanwhile, US officials told Reuters that Russia had also been shooting cruise missiles from assets in the Mediterranean Sea, for the first time since the start of its military intervention in Syria on 30 September.
The Syrian Observatory for Human Rights reported that six missiles had struck areas on "on the road connecting the villages of Ehsim and al-Barra, as well as other areas in Jabal al-Zawiya and the village of al-Sahn near Jisr al-Shughur".
"This caused injuries and material damage to civilian property," said the Observatory.
Meanwhile, in the Hama province, the monitoring NGO said that "what was thought to be a ballistic missile hit an area [near] the village of Sarireef to the west of Hama".
"News has also emerged of the death of four civilians and the injury [of others] due to a suspected ballistic missile strike on areas in the village of Midan al-Ghazal in rural Hama's Jabal Shahshabo [area] this morning."
Activist media further reported on the Russian missile strikes throughout northwest Syria, with Shaam News saying that a barrage rocked Idlib's Jabal al-Zawiya area.
Fierce fighting continued across multiple parts of Syria during Friday. Many observers believe the conflict is only likely to escalate further, as warring parties vie to improve their negotiating hands ahead of the next round of the Vienna peace talks.