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Asma al-Assad, whose father is a cardiologist and whose mother is a diplomat, has two sons and a daughter with Assad.
Born in 1975 in Britain, the former investment banker styled herself as a progressive rights advocate and the modern face of the Assad family, which has ruled Syria with an iron fist since 1970.
However, she has supported her husband through the brutal suppression of pro-democracy demonstrations and the bloody conflict which followed, in which more than 500,000 Syrians were killed, mostly as a result of regime bombardment of civilian areas.
In 2012, leaked emails revealed that she had spent £250,000 on lavish furniture and £5,000 on crystal-encrusted heels, while Syrian cities were being devastated by the Assad regime.
Many Syrians consider her complicit in Bashar al-Assad’s war, and there have been calls for her British citizenship to be revoked.
The international fashion industry distanced itself from the Assad family. Anna Wintour, the editor-in-chief of Vogue apologised for an interview published prior to the Syrian revolution in which Asma was described as a "desert rose".
"Subsequent to our interview, as the terrible events of the past year and a half unfolded in Syria, it became clear that its priorities and values were completely at odds with those of Vogue," Wintour said.
"The escalating atrocities in Syria are unconscionable and we deplore the actions of the Assad regime in the strongest possible terms."
The interview was paid for by the Assad regime as part of a public relations offensive.
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